Shaun Murphy, a young surgeon with autism and savant syndrome, relocates from a quiet country life to join a prestigious hospital's surgical unit. Unable to personally connect with those around him, Shaun uses his extraordinary medical gifts to save lives and challenge the skepticism of his colleagues.

• Freddie Highmore
• Fiona Gubelmann
• Will Yun Lee
• Christina Chang
• Paige Spara
• Bria Samoné Henderson
• Noah Galvin
• Chuku Modu